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Postdoctoral Position in Signal Transduction and Transcriptional Regulation at UCLA

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Position overview

Position title: Postdoc Scholar

Position description

Postdoctoral Position in Signal Transduction and Transcriptional Regulation at UCLA
The laboratories of Dr. Elaine Reed (Immunogenetics Center, Department of Pathology and Laboratory Medicine) and Dr. Enrique Rozengurt (Signal Transduction Laboratory, Department of Medicine) in the David Geffen School of Medicine at UCLA are seeking applications for full-time Postdoctoral Positions.

The focus of the projects will be to study the mechanisms of HLA class I and class II antibody-mediated graft injury leading to chronic antibody-mediated rejection (cAMR) with the aim of identifying potential therapeutic targets to prevent cAMR. These studies will include: 1) The role of the YAP/TAZ transcriptional program in promoting the proliferation and migration of endothelial cells (ECs) in response to HLA donor specific antibodies. 2) To investigate the mechanism(s) by which statins inhibit YAP function, proliferation and migration of ECs. 3) Characterize the impact of statins on YAP activity and cAMR in vivo using a novel model of heart graft allograft that develop transplant vasculopathy (TV).

The candidate, a recent PhD, MD or DVM, must be enthusiastic, have strong written and oral communication skills, be highly motivated, intellectually creative, able to work independently, and function well as part of a team. Candidates will be expected to contribute to ongoing projects and expand novel independent research projects in a collaborative research environment.

The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status. For the complete University of California nondiscrimination and affirmative action policy, see: UC Nondiscrimination & Affirmative Action Policy.

Applying for the position
Interested applicants should submit their CV as well as a cover letter indicating how their past research experience, interests, and goals connect to the activities of the laboratory. The letter should also include the names and contact information for three references.
Please submit to: https://recruit.apo.ucla.edu/JPF06768.

Deadline for applications: May 20, 2022

Qualifications

Basic qualifications (required at time of application)

Ph.D. candidate or recent Ph.D. graduate or M.D./Ph.D.

Application Requirements

Document requirements
  • Curriculum Vitae - Your most recently updated C.V.

  • Cover Letter (Optional)

  • Statement of Research (Optional)

  • Statement of Teaching (Optional)

  • Statement on Contributions to Equity, Diversity, and Inclusion - An EDI Statement describes a faculty candidate’s past, present, and future (planned) contributions to equity, diversity, and inclusion. To learn more about how UCLA thinks about contributions to equity, diversity, and inclusion, please review our Sample Guidance for Candidates and related EDI Statement FAQ document.

  • Misc / Additional (Optional)

Reference requirements
  • 3 letters of reference required

Please submit 3 letters of recommendation

Apply link: https://recruit.apo.ucla.edu/JPF06768

Help contact: kfisher@mednet.ucla.edu

About UCLA

As a University employee, you will be required to comply with all applicable University policies and/or collective bargaining agreements, as may be amended from time to time. Federal, state, or local government directives may impose additional requirements.

The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status. For the complete University of California nondiscrimination and affirmative action policy, see: UC Nondiscrimination & Affirmative Action Policy.