Open date: September 1st, 2021
Last review date: Friday, Sep 17, 2021 at 11:59pm (Pacific Time)
Applications received after this date will be reviewed by the search committee if the position has not yet been filled.
Final date: Thursday, Mar 31, 2022 at 11:59pm (Pacific Time)
Applications will continue to be accepted until this date, but those received after the review date will only be considered if the position has not yet been filled.
The laboratories of Drs. Guido Eibl in the Department of Surgery and Enrique Rozengurt in the Division of Digestive Diseases at the David Geffen School of Medicine are seeking applicants for a full-time Postdoctoral Scholar position. The proposed project is part of a recently funded 5-year NIH Program Project Grant on “Chemoprevention and mechanisms of obesity-promoted pancreatic adenocarcinoma (PDAC)”. Current projects focus on the role of YAP/TAZ transcriptional co-activators in diet-induced obesity and PDAC. These studies include investigating the underlying mechanisms that inflammation plays in the link between obesity and cancer, to identify the molecular mechanism, by which statins inhibit YAP/TEAD signaling in mouse and human pancreatic cells, and to characterize the inhibitory effect of statin and metformin on the development of PDAC as a novel chemopreventive strategy. Experiments are carried out in cell culture and genetically engineered mouse models. This position offers a unique opportunity to gain expertise in both signal transduction mechanisms in pancreatic cancer and a highly relevant preclinical model of this disease.
The candidate must be enthusiastic, have strong written and oral communication skills, be highly motivated, intellectually creative, able to work independently, and function well as part of a team. Candidates will be expected to contribute to ongoing projects and expand novel independent research projects in a collaborative research environment. A Ph.D, MD, or DVM is required.
A PhD, DVM or MD is required
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