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We are seeking a researcher to join the Soragni Lab as a Project Scientist. The Project Scientist works independently and in cooperation with the Principal Investigator, team members and collaborators to make significant and creative contributions to our research project focused on investigating p53 aggregation in ovarian cancer in vitro and in vivo. The Project Scientist will be responsible for coordinating in vivo experiments, breeding, genotyping and treatment as well as sample procurement and processing for both mouse and human samples. The Project Scientist will also be responsible to train undergraduate and graduate students to perform animal studies, prepare manuscripts for publications in scientific journals and assist with preparation of grant proposals. The successful candidate should be comfortable with mouse handling. Ability to work independently in a high pace, multi-disciplinary environment is essential for this position.

This position requires a PhD in Cancer Biology, Biochemistry or Biology and at least 1 year of research experience in mouse models. Previous experience handling human tissue is preferred. The Project Scientist position is a non-Senate position for 12-months in the first instance, renewable depending on funding and performance. Step is commensurate with experience.

Start Date: 10/2022

Responsibilities for this position include but are not limited to:

• Coordinate mouse purchasing and breeding, genotyping
• Generate xenografts, monitor progression and overall health, treat with different anti-cancer agents
• Perform necropsies and full characterization of drug progression and therapeutic effects
• Lead studies with mouse and patient samples, coordinate sample procurement, develop tumor organoids and perform characterization (IHC, IF, sequencing, mass spec, screening).
• Contribute to the overall scientific knowledge and skill level of the group through collaborating, teaching, and interacting with group members at all levels.
• Keep up with relevant literature and identify areas of interest to advance the project.
• Work with cross-functional project teams to develop and deploy tools (both laboratory and analysis) to support the project development.
• Mentor undergraduate and graduate to accomplish any of the above tasks.
• Maintain a cutting-edge awareness of technical developments and scientific knowledge and apply these where possible to improve performance and data quality
• Present results of work, interpret data, and draw conclusions in a fully independent manner.
• Communicate clearly and effectively both verbally and in writing and independently write scientific/technical reports and presentations
• Must think critically and work resourcefully to resolve problems
• Ability to multitask and successfully interact with a diverse team of scientists to deliver quality data and results

As a condition of employment, you will be required to comply with the University of California Policy on Vaccination Programs – With Updated Interim Amendments. All Covered Individuals under the policy must provide proof of receiving the COVID-19 Vaccine Primary Series or, if applicable, submit a request for Exception (based on Medical Exemption, Disability, Religious Objection, and/or Deferral based on pregnancy or recent COVID-19 diagnosis and/or treatment) no later than the applicable deadline. All Covered Individuals must also provide proof of receiving the most recent CDC-recommended COVID-19 booster or properly decline such booster no later than the applicable deadline. New University of California employees should refer to Exhibit 2, Section II.C. of the SARS-CoV-2 (COVID-19) Vaccination Program Attachment for applicable deadlines. All Covered Individuals must also provide proof of being Up-To-Date on seasonal influenza vaccination or properly decline such vaccination no later than the applicable deadline. Please refer to the Seasonal Influenza Vaccination Program Attachment. (Capitalized terms in this paragraph are defined in the policy.) Federal, state, or local public health directives may impose additional requirements.

The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status. For the complete University of California nondiscrimination and affirmative action policy, see: UC Nondiscrimination & Affirmative Action Policy.