The Division of Pulmonary and Critical Care, David Geffen School of Medicine at UCLA, has an opening for a full-time Assistant Project Scientist. Start date will be August 2018.
The Assistant Project Scientist candidate will perform independent research on the role of the sodium glucose transporter 2 (SGLT2) in patient-derived and genetically engineered lung adenocarcinoma mouse models. His/her work will focus on 1) establishing a bank of tumor organoids from surgical samples of lung adenocarcinoma, 2) developing in ovo models of organoid growth in the chorioallantoic membrane of fertilized chicken egg for imaging studies (PET, CT, MRI); 3) performing therapeutic trials with SGLT2 inhibitors in tumor organoids and in genetically engineered mouse models: KRas mutant and SGLT2 knockout mice. The Assistant Project Scientist will also be responsible for assisting and supervising junior postdoctoral fellows, graduate students and undergraduate student researchers, preparing manuscripts for publication in scientific journals, and assisting with the preparation of grant proposals.
This position requires a Ph.D. in biomedical sciences and a minimum of 5 years experience in biomedical research with a focus on mouse models of cancer, PET imaging and translational research. The Assistant Project Scientist position is a 12-month, non-Academic Senate position.
Develop concepts, identify or generate reagents, and perform logical series of experiments to develop understanding of role of SGLT2 in lung adenocarcinoma, identify PET probes to guide therapeutic delivery of SGLT2 inhibitors, prepare high-impact publications and assist with grant preparation. Additional responsibilities include: genotyping mice, induction of lung tumors in mice, performing micro PET and CT imaging on mice, daily dosing of mice, euthanize moribund mice, harvest of tissue, tissue analysis by biochemical and immunohistological approaches.
• 5 years research experience in molecular and cell biology and 2 years of specific experience in SGLT2 and PET imaging related cancer research in experimental animals and cellular systems.
• Documented experience in recombinant DNA technology, PCR, cell culture techniques, basic biochemistry, immunohistochemistry and mouse models of disease.
• Documented ability to handle several projects simultaneously.
• Documented ability to train, advise and supervise laboratory personnel.
• Documented ability to maintain and supervise the maintenance of high quality scientific records.
• Report directly to the Principal Investigator.
• Carry out experiments and analyze the data generated with minimal supervision.
• Supervise undergraduates, graduate students and new postdoctoral trainees in the lab.
• Work on multiple projects efficiently and effectively.
• Assist with preparation of grant proposals.
• Deliver effective presentations and participate actively in weekly laboratory meetings.
• Prepare manuscripts for publication in scientific journals.
• Communicate effectively with other scientists worldwide.
• Maintain or organize the maintenance of critical equipment
• Organize laboratory safety protocols and inventory systems
The University of California is an Equal Opportunity/Affirmative Action Employer advancing inclusive excellence. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status, or other protected categories covered by the UC nondiscrimination policy. For the complete University of California nondiscrimination and affirmative action policy see: UC Nondiscrimination and Affirmative Action Policy.
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