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The Laboratory of Autophagy and Integrative Physiology in the Division of Digestive Diseases at the University of California Los Angeles is seeking a full-time postdoctoral scholar to understand the mechanisms by which autophagy and autophagy-related acidic vesicles degrade lipid droplets in liver. The postdoctoral scholar will apply complementary approaches including isolation of autophagosomes, autolysosomes and late endosomes, flow cytometry and super-resolution microscopy to determine the mechanisms of sequestration of lipid cargo by autophagy. The position will offer excellent opportunities towards career development, training in various state-of-the-art methods in mouse models, and an understanding of mammalian physiology. The applicant will work directly with Dr. Nuria Martinez-Lopez, Dr. Rajat Singh, and an array of faculty collaborators across UCLA. There will be opportunities to drive high-impact projects and work in a diverse, inclusive and collaborative environment within a highly motivated research team. Extensive mentorship will be provided to facilitate the transition to an independent research career.

Required Qualifications:
An M.D. and/or Ph.D. in biomedical science or a related field is required. Candidates with prior postdoctoral research experience in liver biology/physiology and/or autophagy preferred. The ideal candidate must have a demonstrated publication track record, with at least 1 first-authored paper in a reputable journal, strong verbal and written communication skills, ability to work independently and as part of a team. Experience in molecular biology skills including western blotting, real-time qPCR, immunofluorescence, cell culture, mammalian overexpression systems, in vivo mouse models, and other techniques. Experience with cytometry/FACs is a plus.

The postdoctoral scholar's responsibilities will include, but are not limited to:
• Confocal and super-resolution microscopy
• Isolation of acidic organelles via biochemical approaches
• Various biochemical approaches such as Co-IP and Western blotting, and gene expression analyses
• Analyses of data, preparation of manuscripts, and presentations of findings at meetings, etc.

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As a University employee, you will be required to comply with all applicable University policies and/or collective bargaining agreements, as may be amended from time to time. Federal, state, or local government directives may impose additional requirements.

The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status. For the complete University of California nondiscrimination and affirmative action policy, see: UC Nondiscrimination & Affirmative Action Policy.